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KMID : 0604020150300030171
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Korean Journal of Critical Care Medicine
2015 Volume.30 No. 3 p.171 ~ p.175
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Polymyxin B Hemoperfusion in Pneumonic Septic Shock Caused by Gram-Negative Bacteria
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Yoo Jung-Wan
Park Su-Yeon
Jeon Jin
Huh Jin-Won
Lim Chae-Man
Koh Youn-Suck
Hong Sang-Bum
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Abstract
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Severe sepsis and septic shock are the main causes of death in critically ill patients. Early detection and appropriate treatment according to guidelines are crucial for achieving favorable outcomes. Endotoxin is considered to be a main element in the pathogenic induction of gram-negative bacterial sepsis. Polymyxin B hemoperfusion can remove endotoxin and is reported to improve clinical outcomes in patients with intra-abdominal septic shock, but its clinical efficacy for pneumonic septic shock remains unclear. Here, we report a case of a 51-year-old man with pneumonic septic shock caused by Pseudomonas aeruginosa, who recovered through polymyxin B hemoperfusion.
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KEYWORD
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endotoxin, hemoperfusion, polymyxin B, shock, septic
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